Clofazimine (CFZ) is a poorly soluble, weakly basic, small molecule antibiotic clinically used to treat leprosy and is now in clinical trials as a treatment for multidrug resistant tuberculosis and COVID-19.CFZ exhibits complex, context-dependent pharmacokinetics that are characterized by an increasing half-life in long term treatment regimens.The
Kriteria Rumah Tinggal Ideal Bagi Pengrajin Gerabah di Desa Panjangrejo, Kabupaten Bantul, D.I. Yogyakarta
Panjangrejo village is a tourism village that located in Pundong sub-district, Bantul regency, Yogyakarta Special Region.This village is Bandages an area of pottery production centers where most of the villagers work as pottery craftsmen.This potential is also supported by the Regional Planning and Development Agency (Bappeda) and the Bantul Regenc
Harnessing adenovirus in cancer immunotherapy: evoking cellular immunity and targeting delivery in cell-specific manner
Abstract Recombinant adenovirus (rAd) regimens, including replication-competent oncolytic adenovirus (OAV) and replication-deficient adenovirus, have been identified as potential cancer therapeutics.OAV presents advantages such as selective replication, oncolytic efficacy, and tumor microenvironment (TME) remodeling.In this perspective, the princip